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Latanoprost,XALATAN,ISOPROPYL
Latanoprost
Latanoprost,XALATAN,ISOPROPYL (CAS:130209-82-4) used for controlling the progression of glaucoma or ocular hypertension by reducing intraocular pressure

Name

Latanoprost

CAS

130209-82-4

Synonyms

XALATAN;ISOPROPYL (5Z, 9A,11A,15R)-9,11,15-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OATE;
LATANOPROST;17-PHENYL-13,14-DIHYDRO TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER;9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OIC A

MF

C26H40O5

MW

432.59

Others

Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension by reducing intraocular pressure. It is a prostaglandin analogue (more specifically an analogue of prostaglandin F2α[1]) that works by increasing the outflow of aqueous fluid from the eyes (through the uvealsclearal tract).[2]

It is also known by the brand name of Xalatan manufactured by Pfizer. Annual sales are approximately $1.6 billion. The patent for latanoprost expired in March 2011, and at least one generic version (manufactured by Mylan Inc.) is now widely available in the U.S. The Veterans Health Administration, part of the U.S. Department of Veterans Affairs, uses generic Latanoprost manufactured by Alcon Laboratories of Fort Worth, Texas distributed by Novartis generic brand Sandoz Pharmaceuticals.

Latanoprost was developed by Carl B. Camras and his research adviser László Z. Bitó at Columbia University in 1996.[3]

 

 
 
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